Surface motion prediction and mapping for road infrastructures management by PS-InSAR measurements and machine learning algorithms

This paper introduces a methodology for predicting and mapping surface motion beneath road pavement structures caused by environmental factors. Persistent Scatterer Interferometric Synthetic Aperture Radar (PS-InSAR) measurements, geospatial analyses, and Machine Learning Algorithms (MLAs) are employed for achieving the purpose. Two single learners, i.e., Regression Tree (RT) and Support Vector Machine (SVM), and two ensemble learners, i.e., Boosted Regression Trees (BRT) and Random Forest (RF) are utilized for estimating the surface motion ratio in terms of mm/year over the Province of Pistoia (Tuscany Region, central Italy, 964 km2), in which strong subsidence phenomena have occurred. The interferometric process of 210 Sentinel-1 images from 2014 to 2019 allows exploiting the average displacements of 52,257 Persistent Scatterers as output targets to predict. A set of 29 environmental-related factors are preprocessed by SAGA-GIS, version 2.3.2, and ESRI ArcGIS, version 10.5, and employed as input features. Once the dataset has been prepared, three wrapper feature selection approaches (backward, forward, and bi-directional) are used for recognizing the set of most relevant features to be used in the modeling. A random splitting of the dataset in 70% and 30% is implemented to identify the training and test set. Through a Bayesian Optimization Algorithm (BOA) and a 10-Fold Cross-Validation (CV), the algorithms are trained and validated. Therefore, the Predictive Performance of MLAs is evaluated and compared by plotting the Taylor Diagram. Outcomes show that SVM and BRT are the most suitable algorithms; in the test phase, BRT has the highest Correlation Coefficient (0.96) and the lowest Root Mean Square Error (0.44 mm/year), while the SVM has the lowest difference between the standard deviation of its predictions (2.05 mm/year) and that of the reference samples (2.09 mm/year). Finally, algorithms are used for mapping surface motion over the study area. We propose three case studies on critical stretches of two-lane rural roads for evaluating the reliability of the procedure. Road authorities could consider the proposed methodology for their monitoring, management, and planning activities

Trigeminal sensory pathway function in patients with SUNCT

[IF 2.64] Objective: Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a rare primary headache whose origins are unclear. To seek information on its pathophysiology, we studied the trigeminal Ab and Ad pathways by recording trigeminal reflexes and laser evoked potentials (LEPs) in patients with SUNCT. Methods: Trigeminal reflexes and LEPs were recorded in 11 consecutive patients. Ten patients had neuroimaging evidence documenting idiopathic SUNCT and one had a posterior fossa tumour that compressed the trigeminal nerve thus causing symptomatic SUNCT. Results: Whereas the patients with idiopathic SUNCT had normal trigeminal reflex and LEP responses, the patient with symptomatic SUNCT had abnormal responses. Conclusions: Our neurophysiological findings show that idiopathic SUNCT spares the trigeminal sensory pathways whereas symptomatic SUNCT does not. Significance: Neurophysiological testing can easily differentiate the idiopathic and symptomatic forms of SUNCT. It also suggests that the two forms are pathophysiologically distinct entities

Iatrogenic damage to the mandibular nerves as assessed by the masseter inhibitory reflex

Iatrogenic injury of the inferior alveolar or lingual nerves frequently leads to legal actions for damage and compensation for personal suffering. The masseter inhibitory reflex (MIR) is the most used neurophysiological tool for the functional assessment of the trigeminal mandibular division. Aiming at measuring the MIR sensitivity and specificity, we recorded this reflex after mental and tongue stimulations in a controlled, blinded study in 160 consecutive patients with sensory disturbances following dental procedures. The MIR latency was longer on the affected than the contralateral side (P < 0.0001). The overall specificity and sensitivity were 99 and 51%. Our findings indicate that MIR testing, showing an almost absolute specificity, reliably demonstrates nerve damage beyond doubt, whereas the relatively low sensitivity makes the finding of a normal MIR by no means sufficient to exclude nerve damage. Probably, the dysfunction of a small number of nerve fibres, insufficient to produce a MIR abnormality, may still engender important sensory disturbances. We propose that MIR testing, when used for legal purposes, be considered reliable in one direction only, i.e. abnormality does prove nerve damage, normality does not disprove it

PREVALENCE OF BYOGENES AMMINS IN SEASONED D.O.P. CHEESE TOSCANO PECORINO

Pecorino cheese is one of the &ldquo;D.O.P.&rdquo; products made in Tuscany. There are two types of pecorino cheese one of which undergoes a curing time period which is not less than four months. Considering this curing time period, processes are conceivable that could lead to the formation of amines such as free amino acids. The biogenic amines have unquestionable effects on health in particular histamine and tyramine, they are also important indicators of hygienic quality of the profile of the movement shortly after the curing time period and included in the shelf life period which the product is commercialized

A Naturally Narrow Positive Parity Theta^+

We present a consistent color-flavor-spin-orbital wave function for a positive parity Theta^+ that naturally explains the observed narrowness of the state. The wave function is totally symmetric in its flavor-spin part and totally antisymmetric in its color-orbital part. If flavor-spin interactions dominate, this wave function renders the positive parity Theta^+ lighter than its negative parity counterpart. We consider decays of the Theta^+ and compute the overlap of this state with the kinematically allowed final states. Our results are numerically small. We note that dynamical correlations between quarks are not necessary to obtain narrow pentaquark widths.Comment: 10 pages, 1 figure, Revtex4, two-column format, version to be published in Phys. Rev. D, includes numerical estimates of decay width

Sicurezza e Resilienza delle Infrastrutture

Negli ultimi anni si sono manifestati eventi calamitosi che hanno causato collassi, completi o parziali nelle reti infrastrutturali in numerose aree nel mondo. A fronteggiare tali calamità intervengono la pubblica amministrazione e/o i gestori della rete che, collaborando a volte anche con associazioni e organizzazioni private e di volontariato, operano per ripristinare le prestazioni originarie del sistema. In particolar modo le infrastrutture critiche, cioè quei sistemi legati ai servizi di comunicazione, distribuzione dell’energia, sanità, tecnologia dell’informazione, sistemi finanziari/bancari, trasporti e sistemi idrici che forniscono i servizi essenziali per l’economia, la sicurezza e la stabilità di una Nazione, devono essere salvaguardate dai disastri. Il sistema di trasporto è essenziale per il benessere delle comunità, specialmente in condizioni avverse in quanto fornisce la possibilità di evacuazione, delle operazioni di salvataggio e facilita il ripristino dei servizi per la comunità, data la sua vasta interconnessione con tutte le altre infrastrutture critiche. Le caratteristiche e la capacità di un determinato territorio atte a fronteggiare gli eventi calamitosi dipendono da numerosi aspetti che possono essere riassunti nei concetti di sostenibilità, vulnerabilità e resilienza. Gli approcci definiti come disaster risk, climate change e quello basato sulla resilienza sono gli strumenti di valutazione maggiormente utilizzati e innovativi. La recente introduzione di questi concetti e degli approcci citati comporta un ventaglio di definizioni non univoche nella letteratura tecnica. Il presente lavoro ha lo scopo di: 1) Fornire una revisione critica e comparata della letteratura tecnica sull’argomento; 2) Analizzare gli attuali approcci che mirano ad incrementare la resilienza di una infrastruttura legata al trasporto, in particolar modo nei confronti di eventi rari (es. alluvioni, frane, ecc.); 3) Individuare i fattori e le azioni che influiscono sul ripristino delle performance del sistema; 4) Elaborare un metodo di valutazione della resilienza di tipo gerarchico

Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR &lt; 60 mL/min/1.73 m2) or eGFR reduction &gt; 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR &lt; 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR &gt; 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening

Italian guidelines for primary headaches: 2012 revised version

The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in adults was published in J Headache Pain 2(Suppl. 1):105–190 (2001). Ten years later, the guideline committee of the Italian Society for the Study of Headaches (SISC) decided it was time to update therapeutic guidelines. A literature search was carried out on Medline database, and all articles on primary headache treatments in English, German, French and Italian published from February 2001 to December 2011 were taken into account. Only randomized controlled trials (RCT) and meta-analyses were analysed for each drug. If RCT were lacking, open studies and case series were also examined. According to the previous edition, four levels of recommendation were defined on the basis of levels of evidence, scientific strength of evidence and clinical effectiveness. Recommendations for symptomatic and prophylactic treatment of migraine and cluster headache were therefore revised with respect to previous 2001 guidelines and a section was dedicated to non-pharmacological treatment. This article reports a summary of the revised version published in extenso in an Italian version